RNA interference (RNAi)

Posted on September 10th, 2010 Dan

Biotech breakthru could allow temporary control over gene expression

Zero Hedge

.. As the name implies, the technique involves interrupting the function of RNA (ribonucleic acid), one of the key components of all living cells.

Once genetic mapping became a reality, researchers quickly discovered that it was possible to sabotage wayward mRNA before it ever gets to the ribosome. All you had to do was synthesize the anti-sense form of the undesirable mRNA and inject it into the cell, where it would bond with the sense sequence automatically, effectively “switching off” the message. If the ribosome can’t read it, you’ve achieved RNA interference, and the offending proteins will never be produced at all.

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